SCHEMBL303175

SCHEMBL303175

Cn1cc(C(=O)Nc2ccccc2-c2cc(F)c(F)c(F)c2)c(C(F)Cl)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 3/20 0.46
ATM Q13315 1/20 0.42
NTRK1 P04629 3/20 0.42
CHRM2 P08172 1/20 0.40
CHRM1 P11229 1/20 0.40
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 4/20 0.40
HTT P42858 2/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
POLB P06746 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
JAK2 O60674 1/20 0.38
JAK1 P23458 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390454 1.00 CHRM3 (0.46) CHRM3ATMNTRK1CHRM2CHRM1
SCHEMBL16617799 0.97 CHRM3 (0.44) CHRM3ATMNTRK1CHRM2CHRM1
SCHEMBL17892713 0.92 NTRK1 (0.41) CHRM3ATMNTRK1CHRM2CHRM1
SCHEMBL29353394 0.92 CHRM3 (0.47) CHRM3ATMNTRK1CHRM2CHRM1
SCHEMBL167627 0.92 CHRM3 (0.47) CHRM3ATMNTRK1CHRM2CHRM1
SCHEMBL4909628 0.91 CHRM3 (0.47) CHRM3ATMNTRK1KDM4EALDH1A1
SCHEMBL4921835 0.90 SSTR2 (0.44) CHRM3ATMNTRK1KDM4EALDH1A1
SCHEMBL1092348 0.89 CHRM3 (0.47) CHRM3ATMNTRK1CHRM2CHRM1
SCHEMBL16972354 0.87 CHRM3 (0.39) CHRM3ATMNTRK1KDM4EALDH1A1
SCHEMBL4918770 0.87 CHRM3 (0.50) CHRM3ATMNTRK1CHRM1SUCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 EP claimed
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2017-07-13 US claimed
US-9635854-B2 Controlling red rice with mesotrione FMC CORPORATION (US) 2017-05-02 US claimed
US-9622484-B2 Microbial compositions and methods of use for benefiting plant growth and treating plant disease FMC CORPORATION (US) 2017-04-18 US claimed
US-20160183537-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
US-20160183538-A1 MICROBIAL COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
US-20160186273-A1 BACILLUS AMYLOLIQUEFACIENS RTI301 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
US-20150313235-A1 Method for Controlling Weeds Using Formulations Containing Fluthiacet-Methyl and HPPD Herbicides FMC CORP (US) 2015-11-05 US claimed
WO-2009063075-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2009-05-22 WO claimed
WO-2009040397-A1 TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL BASF SE (DE) 2009-04-02 WO claimed
WO-2009007233-A2 PESTICIDAL MIXTURES COMPRISING SULFONAMIDES AND ONE OR MORE FUNGICIDES BASF SE (DE) 2009-01-15 WO claimed
WO-2008148859-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2008-12-11 WO claimed
US-20080293798-A1 Fungicidal Mixtures Comprising Substituted 1-Methylpyrazol-4-Ylcarboxanilides BASF AKTIENGELSELLSCHAFT (DE) 2008-11-27 US claimed
WO-2008098928-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2008-08-21 WO claimed
WO-2008095913-A2 PESTICIDAL MIXTURES BASF SE (DE) 2008-08-14 WO claimed
US-20080153707-A1 Pyrazolecarboxanilides, Process for Their Preparation and Compositions Comprising Them for Controlling Harmful Fungi BASF AKITENGESELLSCHAFT (DE) 2008-06-26 US claimed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160186273-A1 BACILLUS AMYLOLIQUEFACIENS RTI301 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE BTF3, MYB, AGXT CHRM3 489/4885ATM 1857/4885NTRK1 862/4885
US-20080153707-A1 Pyrazolecarboxanilides, Process for Their Preparation and Compositions Comprising Them for Controlling Harmful Fungi CBR3, C1S, PYM1 CHRM3 222/4885ATM 2473/4885NTRK1 4602/4885
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC CHRM3 487/4885ATM 1922/4885NTRK1 633/4885
US-20080293798-A1 Fungicidal Mixtures Comprising Substituted 1-Methylpyrazol-4-Ylcarboxanilides CBR3, CBR1, CTRL CHRM3 417/4885ATM 3884/4885NTRK1 3385/4885
US-20160183537-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC CHRM3 487/4885ATM 1922/4885NTRK1 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.