SCHEMBL30317543

SCHEMBL30317543

CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 7/20 0.60
NPY1R P25929 5/20 0.60
NPY2R P49146 3/20 0.60
FOLH1 Q04609 1/20 0.54
OPRD1 P41143 3/20 0.54
OPRM1 P35372 1/20 0.54
IL1RN P18510 1/20 0.53
ERAP2 Q6P179 1/20 0.53
NPY5R Q15761 2/20 0.53
KISS1R Q969F8 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30473782 0.96 NPY4R (0.59) NPY4RNPY1RNPY2ROPRD1OPRM1
SCHEMBL29575832 0.96 NPY4R (0.60) NPY4RNPY1RNPY2RFOLH1OPRD1
SCHEMBL30745233 0.92 IL1RN (0.59) NPY4RNPY1RNPY2RFOLH1OPRD1
SCHEMBL32670339 0.92 NPY4R (0.57) NPY4RNPY1RNPY2RFOLH1OPRD1
SCHEMBL29630754 0.91 NAALAD2 (0.54) NPY4RNPY1RNPY2RERAP2
SCHEMBL29591937 0.91 NAALAD2 (0.54) NPY4RNPY1RNPY2RERAP2
SCHEMBL5970485 0.91 NAALAD2 (0.56) NPY4RNPY1RNPY2ROPRD1OPRM1
SCHEMBL2488237 0.91 NAALAD2 (0.56) NPY4RNPY1RNPY2ROPRD1OPRM1
SCHEMBL30656938 0.90 NPY4R (0.55) NPY4RNPY1RNPY2ROPRD1OPRM1
SCHEMBL31672190 0.90 NPY4R (0.60) NPY4RNPY1RNPY2RIL1RNERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003336-B PD-1 single domain antibody, nucleotide sequence and kit 深圳普瑞金生物药业股份有限公司 2023-05-12 CN disclosed