SCHEMBL29575832

SCHEMBL29575832

CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 7/20 0.60
NPY1R P25929 5/20 0.60
NPY2R P49146 3/20 0.60
FOLH1 Q04609 1/20 0.57
OPRD1 P41143 3/20 0.54
NPY5R Q15761 2/20 0.53
OPRM1 P35372 1/20 0.51
LTA4H P09960 1/20 0.51
IL1RN P18510 1/20 0.51
ERAP2 Q6P179 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32670339 0.96 NPY4R (0.57) NPY4RNPY1RNPY2RFOLH1OPRD1
SCHEMBL30317543 0.96 NPY4R (0.60) NPY4RNPY1RNPY2RFOLH1OPRD1
SCHEMBL30473782 0.94 NPY4R (0.59) NPY4RNPY1RNPY2ROPRD1NPY5R
SCHEMBL30714766 0.93 OPRD1 (0.57) NPY4RNPY1RNPY2RFOLH1OPRD1
SCHEMBL29531691 0.92 NPY4R (0.59) NPY4RNPY1RNPY2RFOLH1OPRD1
SCHEMBL30061881 0.91 NPY4R (0.63) NPY4RNPY1RNPY2RFOLH1NPY5R
SCHEMBL2184740 0.91 NPY4R (0.66) NPY4RNPY1RNPY2RFOLH1OPRD1
SCHEMBL30544311 0.91 LTA4H (0.62) OPRD1OPRM1LTA4H
SCHEMBL29630754 0.91 NAALAD2 (0.54) NPY4RNPY1RNPY2RERAP2
SCHEMBL29591937 0.91 NAALAD2 (0.54) NPY4RNPY1RNPY2RERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110325544-B Peptide fragment derived from insulin A chain and pharmaceutical composition for preventing or treating diabetes or diabetic wound comprising the same 舒帕得力克瑞股份有限公司 2023-06-27 CN disclosed
US-11312974-B2 Gene for increasing plant biomass and use therefor KANEKA CORPORATION (JP) 2022-04-26 US disclosed