SCHEMBL30317554

SCHEMBL30317554

O=C(C=Cc1ccccc1-c1ccccc1)C=Cc1ccccc1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.58
NFKB1 P19838 3/20 0.57
NFE2L2 Q16236 2/20 0.57
JUN P05412 1/20 0.57
HSD11B1 P28845 1/20 0.55
PTGER1 P34995 2/20 0.53
PTGER3 P43115 2/20 0.53
PTGER2 P43116 2/20 0.53
MAPT P10636 2/20 0.52
PLIN1 O60240 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
F3 P13726 1/20 0.52
RECQL P46063 1/20 0.52
PLIN5 Q00G26 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
ABHD5 Q8WTS1 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28993515 0.89 GSR (0.60) BACE1NFKB1NFE2L2JUNHSD11B1
SCHEMBL2433472 0.88 PTGER3 (0.66) BACE1NFKB1PTGER1PTGER3PTGER2
SCHEMBL181054 0.88 PTGER3 (0.66) BACE1NFKB1PTGER1PTGER3PTGER2
Hydrochloric Acid SCHEMBL11527565 0.86 PTGER3 (0.64) BACE1NFKB1PTGER1PTGER3PTGER2
SCHEMBL6835912 0.85 BACE1 (0.55) BACE1NFKB1NFE2L2JUNPTGER1
SCHEMBL27642891 0.85 BACE1 (0.55) BACE1NFKB1NFE2L2JUNPTGER1
SCHEMBL6835913 0.85 BACE1 (0.55) BACE1NFKB1NFE2L2JUNPTGER1
SCHEMBL3667411 0.85 BACE1 (0.55) BACE1NFKB1NFE2L2JUNPTGER1
SCHEMBL9240254 0.83 MAPT (0.57) BACE1NFKB1PTGER1PTGER3PTGER2
SCHEMBL9240252 0.83 MAPT (0.57) BACE1NFKB1PTGER1PTGER3PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024060641-A1 CYCLOTRIARYLPHOSPHINE, METHOD FOR PREPARING SAME, AND USE THEREOF 东莞市均成高新材料有限公司 2024-03-28 WO disclosed
CN-115850329-A Cycloterpyriaryl phosphines, their preparation and use 东莞市均成高新材料有限公司 2023-03-28 CN disclosed