Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.81 |
| ▸ | HDAC1 | Q13547 | 19/20 | 0.81 |
| ▸ | HDAC8 | Q9BY41 | 18/20 | 0.81 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.68 |
| ▸ | MELK | Q14680 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24031120 | 0.89 | HDAC6 (1.00) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317740 | 0.87 | HDAC6 (0.77) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317704 | 0.86 | HDAC6 (0.80) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317678 | 0.85 | HDAC6 (0.78) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317705 | 0.84 | HDAC6 (0.68) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24031223 | 0.83 | HDAC6 (0.75) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24030765 | 0.83 | HDAC6 (0.88) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24247607 | 0.81 | HDAC1 (0.73) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317719 | 0.81 | HDAC6 (0.80) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24030777 | 0.81 | HDAC6 (0.78) | HDAC6HDAC1HDAC8HDAC11MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621317-B | Inhibitors of Histone Deacetylase (HDACS) | 安基生技新药股份有限公司 | 2023-05-12 | — | — | CN | disclosed |