Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MELK | Q14680 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30317704 | 0.86 | HDAC6 (0.80) | HDAC1HDAC8HDAC6MAPTHDAC11 | |
| SCHEMBL24247592 | 0.86 | MAPT (0.84) | HDAC1HDAC8HDAC6MAPTGAA | |
| SCHEMBL24031120 | 0.84 | HDAC6 (1.00) | HDAC1HDAC8HDAC6HDAC11MELK | |
| SCHEMBL24031181 | 0.84 | THRB (0.71) | HDAC1HDAC8HDAC6MAPTGAA | |
| SCHEMBL24030777 | 0.82 | HDAC6 (0.78) | HDAC1HDAC8HDAC6HDAC11TP53 | |
| SCHEMBL30317680 | 0.81 | HDAC6 (0.81) | HDAC1HDAC8HDAC6HDAC11MELK | |
| SCHEMBL24031223 | 0.81 | HDAC6 (0.75) | HDAC1HDAC8HDAC6MAPTHDAC11 | |
| SCHEMBL24247586 | 0.81 | HDAC1 (0.69) | HDAC1HDAC8HDAC6MAPTHDAC11 | |
| SCHEMBL16674525 | 0.79 | TSHR (0.73) | HDAC1HDAC8HDAC6MAPTGAA | |
| Hydrochloric Acid SCHEMBL29381790 | 0.78 | HDAC6 (0.70) | HDAC1HDAC8HDAC6HDAC11TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3624804-B1 | HISTONE DEACETYLASES (HDACS) INHIBITORS | ANNJI PHARM CO LTD (TW) | 2022-02-16 | — | — | EP | disclosed |