Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24031017 | 1.00 | TP53 (0.62) | TP53MAPTHDAC1HDAC6HDAC2 | |
| SCHEMBL24031014 | 0.90 | PGR (0.65) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL30317687 | 0.89 | PGR (0.57) | TP53HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL24031012 | 0.89 | PGR (0.57) | TP53HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL24031069 | 0.88 | HDAC1 (0.73) | MAPTHDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL30317751 | 0.88 | HDAC1 (0.73) | MAPTHDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL24031071 | 0.85 | HDAC1 (0.75) | TP53MAPTHDAC1HDAC6HDAC8 | |
| SCHEMBL24030783 | 0.82 | HDAC6 (0.53) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL24247594 | 0.81 | TP53 (0.65) | TP53MAPTHDAC1HDAC6HDAC8 | |
| SCHEMBL24247596 | 0.78 | PGR (0.60) | TP53MAPTHDAC1HDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621317-B | Inhibitors of Histone Deacetylase (HDACS) | 安基生技新药股份有限公司 | 2023-05-12 | — | — | CN | disclosed |