Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.76 |
| ▸ | HDAC1 | Q13547 | 16/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 16/20 | 0.76 |
| ▸ | HDAC11 | Q96DB2 | 13/20 | 0.76 |
| ▸ | MELK | Q14680 | 1/20 | 0.76 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24031144 | 0.86 | HDAC6 (1.00) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317704 | 0.86 | HDAC6 (0.80) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24031214 | 0.83 | HDAC6 (0.74) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24031180 | 0.83 | MAPT (0.70) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24031181 | 0.83 | THRB (0.71) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317740 | 0.82 | HDAC6 (0.77) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24031113 | 0.82 | HDAC6 (0.92) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24247605 | 0.82 | HDAC6 (0.67) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24030718 | 0.81 | HDAC6 (0.76) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24031155 | 0.81 | HDAC6 (0.86) | HDAC6HDAC1HDAC8HDAC11MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621317-B | Inhibitors of Histone Deacetylase (HDACS) | 安基生技新药股份有限公司 | 2023-05-12 | — | — | CN | disclosed |