Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | STK10 | O94804 | 1/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23040349 | 1.00 | SIRT2 (0.39) | SIRT2SIRT1EPHX2AKR1C3MGLL | |
| SCHEMBL10044314 | 0.89 | GAA (0.42) | GAAEGFRPDK2NPSR1BRAF | |
| SCHEMBL23040350 | 0.86 | PDK2 (0.36) | GAAPDK2KDM4EMEN1ALDH1A1 | |
| SCHEMBL23065289 | 0.85 | BRD4 (0.32) | PDK2MAPTBRD4 | |
| SCHEMBL26900008 | 0.84 | PTGER4 (0.39) | EPHX2GAAEGFRPDK2NPSR1 | |
| SCHEMBL23040346 | 0.84 | GAA (0.42) | GAAEGFRPDK2NPSR1KDM4E | |
| SCHEMBL17194808 | 0.82 | PDK2 (0.43) | SIRT2SIRT1EPHX2MGLLGAA | |
| SCHEMBL30318845 | 0.82 | PDK2 (0.43) | SIRT2SIRT1EPHX2MGLLGAA | |
| SCHEMBL22182363 | 0.82 | PDK2 (0.46) | SIRT2SIRT1MGLLSYKPDK2 | |
| SCHEMBL29440300 | 0.82 | PDK2 (0.49) | SIRT2SIRT1EPHX2MGLLSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112430190-B | Aromatic amine derivative and organic electroluminescent device comprising same | 北京夏禾科技有限公司 | 2023-04-18 | — | — | CN | disclosed |