SCHEMBL23040346

SCHEMBL23040346

Cc1cc2c(cc1Nc1ccccc1)C(C)(C)c1ccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 6/20 0.42
▸ ALDH1A1 P00352 5/20 0.38
▸ KMT2A Q03164 5/20 0.38
▸ KDM4E B2RXH2 5/20 0.38
▸ MAPT P10636 5/20 0.38
▸ MEN1 O00255 4/20 0.38
▸ CYP3A4 P08684 3/20 0.38
▸ TDP1 Q9NUW8 3/20 0.38
▸ HPGD P15428 3/20 0.38
▸ EGFR P00533 3/20 0.38
▸ SRC P12931 3/20 0.38
▸ LMNA P02545 3/20 0.38
▸ MAPK1 P28482 2/20 0.38
▸ NPSR1 Q6W5P4 2/20 0.38
▸ GLA P06280 2/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ RGS12 O14924 1/20 0.38
▸ GMNN O75496 1/20 0.38
▸ PRKD3 O94806 1/20 0.38
▸ PRKCG P05129 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10044314 0.94 GAA (0.42) GAAALDH1A1KMT2AKDM4EMAPT
SCHEMBL26900008 0.92 PTGER4 (0.39) GAAALDH1A1KMT2AKDM4EMAPT
SCHEMBL30318897 0.84 SIRT2 (0.39) GAAALDH1A1KMT2AKDM4EMAPT
SCHEMBL23040349 0.84 SIRT2 (0.39) GAAALDH1A1KMT2AKDM4EMAPT
SCHEMBL26660392 0.84 MAPT (0.37) GAAALDH1A1KMT2AKDM4EMAPT
SCHEMBL30612824 0.84 MAPT (0.37) GAAALDH1A1KMT2AKDM4EMAPT
SCHEMBL30714373 0.84 MEN1 (0.37) GAAALDH1A1KMT2AKDM4EMAPT
SCHEMBL23040363 0.84 MEN1 (0.37) GAAALDH1A1KMT2AKDM4EMAPT
SCHEMBL12319862 0.82 PDK2 (0.34) MAPTTDP1EGFRMAPK1SMN1; SMN2
SCHEMBL30827116 0.82 PDK2 (0.36) GAAALDH1A1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11937499-B2 Aromatic amine derivative and organic electroluminescent devices containing the same Beijing Summer Sprout Technology Co., Ltd. (CN) 2024-03-19 — — US disclosed
CN-112430190-B Aromatic amine derivative and organic electroluminescent device comprising same 北京夏禾科技有限公司 2023-04-18 — — CN disclosed
US-20210066595-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING THE SAME Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-04 — — US disclosed
US-20210066595-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING THE SAME Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-04 — — US disclosed
CN-112430190-A Aromatic amine derivative and organic electroluminescent device comprising same 北京夏禾科技有限公司 2021-03-02 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210066595-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING THE SAME TYR, DDC, AOC2 GAA 2867/4885ALDH1A1 232/4885KMT2A 102/4885
US-11937499-B2 Aromatic amine derivative and organic electroluminescent devices containing the same TYR, DDC, AOC2 GAA 2867/4885ALDH1A1 232/4885KMT2A 102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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