Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 3/20 | 0.64 |
| ▸ | CTSL | P07711 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.60 |
| ▸ | MYC | P01106 | 1/20 | 0.57 |
| ▸ | MAX | P61244 | 1/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.56 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3026633 | 0.87 | CTSV (0.67) | CTSVCTSLMAPTKMT2AMEN1 | |
| SCHEMBL9463730 | 0.81 | MYC (0.63) | CTSVCTSLMAPTKMT2AMEN1 | |
| SCHEMBL3020950 | 0.81 | MAPT (0.72) | CTSVCTSLMAPTKMT2AMEN1 | |
| SCHEMBL3031833 | 0.80 | CTSV (0.71) | CTSVCTSLMAPTKMT2AMEN1 | |
| SCHEMBL354532 | 0.78 | CTSV (1.00) | CTSVCTSLMAPTKMT2AMEN1 | |
| SCHEMBL22720195 | 0.78 | CTSV (0.78) | CTSVCTSLMAPTKMT2AMEN1 | |
| SCHEMBL4211532 | 0.78 | KMT2A (0.72) | CTSVCTSLMAPTKMT2AMEN1 | |
| SCHEMBL6589180 | 0.77 | HTT (0.63) | CTSVCTSLMAPTKMT2AMEN1 | |
| SCHEMBL3034237 | 0.77 | KMT2A (0.66) | CTSVCTSLMAPTKMT2AMEN1 | |
| SCHEMBL22720188 | 0.77 | MAPT (0.74) | CTSVCTSLMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210654-A1 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN (DE) | 2010-08-19 | — | — | US | disclosed |
| US-20100210654-A1 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN (DE) | 2010-08-19 | — | — | US | disclosed |
| US-20100210654-A1 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN (DE) | 2010-08-19 | — | — | US | disclosed |
| EP-2129653-A2 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008107211-A2 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN (DE) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008107211-A2 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN (DE) | 2008-09-12 | — | — | WO | disclosed |
| EP-1967513-A1 | Novel P2Y12 receptor antagonists | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2008-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210654-A1 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | P2RY12, P2RY11, P2RY13 | CTSV 4711/4885CTSL 3569/4885MAPT 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.