Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 9/20 | 0.60 |
| ▸ | TNKS | O95271 | 2/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22093677 | 1.00 | MAT2A (0.60) | MAT2ATNKSKHKDRD1ALDH1A1 | |
| SCHEMBL31145476 | 0.86 | MAT2A (0.60) | MAT2ATNKSPARP1 | |
| SCHEMBL22093635 | 0.86 | MAT2A (0.60) | MAT2ATNKSPARP1 | |
| SCHEMBL22093620 | 0.84 | MAT2A (0.59) | MAT2ATNKSKHKDRD1PARP1 | |
| SCHEMBL31145391 | 0.84 | MAT2A (0.59) | MAT2ATNKSKHKDRD1PARP1 | |
| SCHEMBL31145580 | 0.84 | MAT2A (0.57) | MAT2ATNKSPARP1 | |
| SCHEMBL31145581 | 0.84 | MAT2A (0.57) | MAT2ATNKSPARP1 | |
| SCHEMBL22093075 | 0.84 | MAT2A (0.57) | MAT2ATNKSPARP1 | |
| SCHEMBL22093235 | 0.83 | MAT2A (0.69) | MAT2AALDH1A1LMNA | |
| SCHEMBL29570284 | 0.83 | MAT2A (0.69) | MAT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867541-A | Aminopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-119528824-A | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-113166078-B | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-115867541-A | Aminopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-03-28 | — | — | CN | disclosed |