SCHEMBL30320108

SCHEMBL30320108

[2H]C([2H])([2H])c1cc2ccccc2o1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.44
CYP2A6 P11509 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
FLT3 P36888 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.44
MGLL Q99685 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA12 O43570 4/20 0.43
CA9 Q16790 4/20 0.43
RAB9A P51151 4/20 0.43
NPC1 O15118 3/20 0.43
TSHR P16473 2/20 0.43
MEN1 O00255 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
HPGD P15428 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
TYR P14679 1/20 0.42
DAO P14920 1/20 0.42
AKR1B1 P15121 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12264 0.84 KDM4E (0.48) KDM4ECYP2A6TDP1FLT3LOXL2
SCHEMBL29670757 0.84 KDM4E (0.48) KDM4ECYP2A6TDP1FLT3LOXL2
Hydrochloric Acid SCHEMBL6013140 0.82 KDM4E (0.47) KDM4ECYP2A6TDP1FLT3LOXL2
Formic Acid SCHEMBL28703391 0.74 CYP2A6 (0.53) KDM4ECYP2A6TDP1FLT3MGLL
Acetic Acid SCHEMBL8595808 0.74 KDM4E (0.54) KDM4EFLT3HSD17B10CA12CA9
Benzofuran SCHEMBL5030467 0.72 CA12 (0.42) KDM4ECYP2A6TDP1FLT3LOXL2
SCHEMBL1009796 0.70 MAOB (0.48) KDM4ECYP2A6TDP1FLT3LOXL2
SCHEMBL28251350 0.70 KDM4E (0.50) KDM4EFLT3HSD17B10CA12CA9
SCHEMBL12326736 0.70 KDM4E (0.44) KDM4ECYP2A6TDP1FLT3LOXL2
SCHEMBL30036439 0.69 MAOB (0.63) KDM4ECYP2A6TDP1FLT3LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063517-A Compound containing 1, 3-diketone ligand, application thereof and organic electroluminescent device 北京绿人科技有限责任公司 2024-05-24 CN disclosed
CN-115974929-A Organic electroluminescent material and device 环球展览公司 2023-04-18 CN disclosed