SCHEMBL12264

SCHEMBL12264

Cc1cc2ccccc2o1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
CYP2A6 P11509 2/20 0.48
FLT3 P36888 1/20 0.48
LOXL2 Q9Y4K0 1/20 0.48
MGLL Q99685 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CA12 O43570 2/20 0.48
CA9 Q16790 2/20 0.48
SMN1; SMN2 Q16637 4/20 0.47
HPGD P15428 3/20 0.47
TYR P14679 1/20 0.47
DAO P14920 1/20 0.47
AKR1B1 P15121 1/20 0.47
POLB P06746 1/20 0.47
RAB9A P51151 4/20 0.46
MAPT P10636 4/20 0.46
ALDH1A1 P00352 3/20 0.46
NPC1 O15118 3/20 0.46
MAOB P27338 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29670757 1.00 KDM4E (0.48) KDM4ECYP2A6FLT3LOXL2MGLL
Hydrochloric Acid SCHEMBL6013140 0.98 KDM4E (0.47) KDM4ECYP2A6FLT3LOXL2MGLL
Acetic Acid SCHEMBL8595808 0.88 KDM4E (0.54) KDM4EFLT3HSD17B10CA12CA9
Formic Acid SCHEMBL28703391 0.88 CYP2A6 (0.53) KDM4ECYP2A6FLT3MGLLHSD17B10
Benzofuran SCHEMBL5030467 0.86 CA12 (0.42) KDM4ECYP2A6FLT3LOXL2MGLL
SCHEMBL30320108 0.84 KDM4E (0.44) KDM4ECYP2A6FLT3LOXL2MGLL
SCHEMBL28251350 0.83 KDM4E (0.50) KDM4EFLT3HSD17B10CA12CA9
SCHEMBL9101203 0.82 FLT3 (0.61) KDM4EFLT3HSD17B10TDP1SMN1; SMN2
Quinoline SCHEMBL27923743 0.82 ALDH1A1 (0.57) KDM4EHSD17B10SMN1; SMN2HPGDPOLB
SCHEMBL14232239 0.81 DYRK1A (0.43) CYP2A6HSD17B10TDP1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3958 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12623986-B2 Synergistic use of phenol purification train in phenol production unit for processing phenolic water from bisphenol-a production unit SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-12 US claimed
EP-4593977-A1 PRODUCTS AND METHODS RELATED TO THE DISTILLATION OF MOLECULES FROM AEROSOLS Natural Extraction Systems, LLC (US) 2025-08-06 EP claimed
US-20250145749-A1 POLY(CYCLIC VINYL ETHERS), COMPOSITIONS OF SAME, METHODS OF MAKING SAME AND USES THEREOF CORNELL UNIVERSITY 2025-05-08 US claimed
CN-119899163-A Diterpenoid component in ethanol extract of lysimachia foenum-graecum as well as extraction method and application thereof 新疆维吾尔自治区中药民族药研究所 2025-04-29 CN claimed
CN-119698277-A Inhibitors of cGAS activity as therapeutic agents 贝尔布鲁克实验室有限责任公司 2025-03-25 CN claimed
CN-119666520-A Pretreatment method for detecting aroma components in main stream smoke of tobacco product 上海烟草集团有限责任公司 2025-03-21 CN claimed
WO-2025050332-A1 AQUEOUS COATING COMPOSITION AND METHOD OF PREPARING THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2025-03-13 WO claimed
EP-4298082-B1 PROCESS FOR PREPARING BISPHENOL A (BPA) IN THE PRESENCE OF AT LEAST TWO IMPURITIES COVESTRO DEUTSCHLAND AG (DE) 2025-03-12 EP claimed
CN-119285968-A Photochromic rare earth polymer and preparation method and application thereof 黑龙江大学 2025-01-10 CN claimed
CN-119242291-A Photochromic rare earth screw and preparation method and application thereof 黑龙江大学 2025-01-03 CN claimed
US-4851086-A SEPARATION WITH ALPHA-METHYLSTYRENE AND METHYLBENZOFURANS AS BY-PRODUCT IMPURTIES THE LUMMUS COMPANY (US) 1989-07-25 US claimed
EP-0301371-A2 Benzofuran carboxamides with basic substituents, process for their preparation and therapeutical compositions containing them BASF Aktiengesellschaft (DE) 1989-02-01 EP claimed
US-4634796-A ACIDIFICATION OF BASE-TREATED PRODUCT AFTER STEAM DISTILLATION LUMMUS CREST, INC. (US) 1987-01-06 US claimed
US-4532012-A Removing methylbenzofuran impurities THE LUMMUS COMPANY (US) 1985-07-30 US claimed
US-4514399-A N-N'substituted polymethylene diamines ADIR (FR) 1985-04-30 US claimed
US-4504364-A METHYLBENZOFURAN REMOVAL, SOLVENT EXTRACTION THE LUMMUS COMPANY (US) 1985-03-12 US claimed
US-4298765-A BASIFICATION, AZEOTROPIC STEAM DISTILLATION, SOLVENT EXTRACTION ALLIED CORPORATION (US) 1981-11-03 US claimed
US-4189410-A DICYCLOPENTADIENE, FATTY ACID, PETROLEUM RESIN, MALEINIZING NEVILLE CHEMICAL COMPANY (US) 1980-02-19 US claimed
US-4113891-A BENZOFURANS FIRMENICH & CIE (CH) 1978-09-12 US claimed
US-4088703-A AS CYCLOHEXANOL; HYDROGENATION USING NICKEL CATALYST, DISTILLATION ALLIED CHEMICAL CORPORATION (US) 1978-05-09 US claimed