SCHEMBL30320186

SCHEMBL30320186

c1ccc2c(c1)Sc1cccc(-c3cccc4c3Sc3ccccc3S4)c1S2

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.66
ATM Q13315 2/20 0.42
PRKDC P78527 2/20 0.41
PIK3CA P42336 1/20 0.41
PIK3CB P42338 1/20 0.41
MTOR P42345 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAOA P21397 2/20 0.39
ADORA3 P0DMS8 2/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A3 Q01959 2/20 0.39
BCHE P06276 2/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
CYP3A4 P08684 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3078569 1.00 ALOX5 (0.66) ALOX5ATMPRKDCPIK3CAPIK3CB
SCHEMBL18034391 0.87 ALOX5 (0.54) ALOX5ATMPRKDCPIK3CAPIK3CB
SCHEMBL10985315 0.86 ALOX5 (0.53) ALOX5ATMPRKDCPIK3CAPIK3CB
SCHEMBL17474342 0.86 ALOX5 (0.58) ALOX5ATMPRKDCPIK3CAPIK3CB
SCHEMBL27541279 0.85 ALOX5 (0.53) ALOX5ATMPRKDCPIK3CAPIK3CB
SCHEMBL19765303 0.85 ALOX5 (0.57) ALOX5ATMPRKDCPIK3CAPIK3CB
SCHEMBL16164512 0.84 ALOX5 (0.51) ALOX5ATMPRKDCPIK3CAPIK3CB
SCHEMBL16166654 0.84 ALOX5 (0.56) ALOX5ATMPRKDCPIK3CAPIK3CB
SCHEMBL16165379 0.83 ALOX5 (0.50) ALOX5ATMPRKDCPIK3CAPIK3CB
SCHEMBL8815969 0.82 ALOX5 (0.50) ALOX5ATMPRKDCPIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388561-A1 A BICYCLOPENTYL THIANTHRENIUM COMPOUND, PROCESS FOR PREPARING THE SAME AND THE USE THEREOF STUDIENGESELLSCHAFT KOHLE GGMBH (DE) 2025-12-25 US disclosed
EP-4399200-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Mitsubishi Gas Chemical Company, Inc. (JP) 2024-07-17 EP disclosed
WO-2023038156-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388561-A1 A BICYCLOPENTYL THIANTHRENIUM COMPOUND, PROCESS FOR PREPARING THE SAME AND THE USE THEREOF BACE1, BACE2, CYP3A43 ALOX5 4273/4885ATM 1650/4885PRKDC 3501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.