Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HCN1 | O60741 | 3/20 | 0.38 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16836038 | 0.88 | HCN1 (0.41) | MEN1KMT2AHDAC9HCN1HCN4 | |
| SCHEMBL12203632 | 0.82 | MEN1 (0.44) | MEN1KMT2AHDAC9POLBL3MBTL1 | |
| SCHEMBL16836097 | 0.80 | KDM4E (0.39) | MEN1KMT2APOLBNOTUMMAPT | |
| SCHEMBL1470334 | 0.80 | MEN1 (0.47) | MEN1KMT2AHDAC9POLBL3MBTL1 | |
| SCHEMBL17027549 | 0.80 | NOTUM (0.46) | MEN1KMT2AL3MBTL1NOTUMMAPT | |
| SCHEMBL16836131 | 0.79 | BRD4 (0.52) | MEN1KMT2APOLBMAPTHTT | |
| SCHEMBL29896401 | 0.79 | CXCR5 (0.41) | MEN1KMT2ANOTUMALDH1A1KDM4E | |
| SCHEMBL28469827 | 0.79 | CXCR5 (0.41) | MEN1KMT2ANOTUMALDH1A1KDM4E | |
| SCHEMBL22729870 | 0.78 | MEN1 (0.42) | MEN1KMT2AHDAC9POLBL3MBTL1 | |
| SCHEMBL1561351 | 0.78 | MEN1 (0.42) | MEN1KMT2AHDAC9POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974808-B | Preparation method of 2-benzyl-7-chloro [1,2-e ] indeno [1,3,4] oxadiazine dimethyl ester | 大连奇凯医药科技有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-115974808-A | Preparation method of 2-benzyl-7-chlorine [1,2-e ] indeno [1,3,4] oxadiazine methyl diformate | 大连奇凯医药科技有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115974808-B | Preparation method of 2-benzyl-7-chloro [1,2-e ] indeno [1,3,4] oxadiazine dimethyl ester | 大连奇凯医药科技有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115974808-B | Preparation method of 2-benzyl-7-chloro [1,2-e ] indeno [1,3,4] oxadiazine dimethyl ester | 大连奇凯医药科技有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115974808-A | Preparation method of 2-benzyl-7-chlorine [1,2-e ] indeno [1,3,4] oxadiazine methyl diformate | 大连奇凯医药科技有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-115974808-A | Preparation method of 2-benzyl-7-chlorine [1,2-e ] indeno [1,3,4] oxadiazine methyl diformate | 大连奇凯医药科技有限公司 | 2023-04-18 | — | — | CN | disclosed |