SCHEMBL30320288

SCHEMBL30320288

O=C(O)CSc1ncnc2c(C3CC3)c(Cl)sc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 17/20 1.00
STK17B O94768 2/20 0.51
MAP3K8 P41279 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439279 1.00 NOTUM (1.00) NOTUMSTK17BMAP3K8
SCHEMBL16333308 0.86 NOTUM (0.76) NOTUM
SCHEMBL438084 0.85 NOTUM (1.00) NOTUMSTK17B
SCHEMBL440706 0.82 NOTUM (1.00) NOTUMSTK17BMAP3K8
SCHEMBL441103 0.80 NOTUM (1.00) NOTUMSTK17BMAP3K8
SCHEMBL16333303 0.78 NOTUM (0.74) NOTUMSTK17BMAP3K8
SCHEMBL441163 0.75 NOTUM (0.59) NOTUM
SCHEMBL16333597 0.74 NOTUM (1.00) NOTUMSTK17BMAP3K8
SCHEMBL438085 0.73 NOTUM (0.77) NOTUMMAP3K8
SCHEMBL439282 0.73 NOTUM (0.56) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680255-A1 METHODS FOR PRODUCING STABLE HUMAN CHONDROCTYES AND THEIR USE FOR PROMOTING CARTILLAGE GROWTH AND REPAIR The United States of America, as represented by the Secretary, Department of Health and Human Services (US) 2026-01-21 EP disclosed
EP-4680969-A1 CANCER STRATIFICATION AND TREATMENT Deutsches Krebsforschungszentrum (DE) 2026-01-21 EP disclosed
WO-2024192329-A1 METHODS FOR PRODUCING STABLE HUMAN CHONDROCTYES AND THEIR USE FOR PROMOTING CARTILLAGE GROWTH AND REPAIR THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-09-19 WO disclosed
WO-2024189200-A1 CANCER STRATIFICATION AND TREATMENT Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2024-09-19 WO disclosed
EP-4153726-A1 METHOD FOR GENERATING FUNCTIONAL SKELETAL MUSCLE FIBERS INNERVATED BY MOTONEURONS Association Française contre les Myopathies (AFM) (FR) 2023-03-29 EP disclosed