Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30319689 | 0.94 | GAA (0.32) | GAASMN1; SMN2IDO1TDO2HRH3 | |
| SCHEMBL31215628 | 0.94 | GAA (0.32) | GAASMN1; SMN2IDO1TDO2HRH3 | |
| SCHEMBL25446966 | 0.86 | — | — | |
| SCHEMBL30142554 | 0.86 | — | — | |
| SCHEMBL20646520 | 0.81 | IDO1 (0.35) | GAASMN1; SMN2IDO1TDO2 | |
| SCHEMBL31073419 | 0.78 | DRD2 (0.33) | GAASMN1; SMN2IDO1TDO2 | |
| SCHEMBL19044201 | 0.76 | IDO1 (0.36) | GAASMN1; SMN2IDO1TDO2 | |
| SCHEMBL16923818 | 0.72 | RECQL (0.35) | GAASMN1; SMN2IDO1TDO2HRH3 | |
| SCHEMBL24146705 | 0.71 | — | — | |
| SCHEMBL30926668 | 0.69 | IDO1 (0.42) | GAASMN1; SMN2IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161494-A1 | NITROGEN-CONTAINING FUSED BICYCLIC COMPOUNDS AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS | KSQ Therapeutics, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |