Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.69 |
| ▸ | HTR2C | P28335 | 4/20 | 0.69 |
| ▸ | DRD2 | P14416 | 3/20 | 0.69 |
| ▸ | DRD3 | P35462 | 3/20 | 0.69 |
| ▸ | HTR2B | P41595 | 3/20 | 0.69 |
| ▸ | HTR6 | P50406 | 3/20 | 0.69 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.69 |
| ▸ | HTR1A | P08908 | 2/20 | 0.69 |
| ▸ | HRH1 | P35367 | 2/20 | 0.69 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.69 |
| ▸ | DRD4 | P21917 | 1/20 | 0.69 |
| ▸ | DRD5 | P21918 | 1/20 | 0.69 |
| ▸ | HTR1D | P28221 | 1/20 | 0.69 |
| ▸ | HTR1E | P28566 | 1/20 | 0.69 |
| ▸ | HTR7 | P34969 | 1/20 | 0.69 |
| ▸ | HTR5A | P47898 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25545392 | 1.00 | HTR2A (0.69) | HTR2AHTR2CDRD2DRD3HTR2B | |
| SCHEMBL30321017 | 0.92 | KDM4E (0.69) | HTR2AHTR2CDRD2DRD3HTR2B | |
| SCHEMBL25545417 | 0.92 | KDM4E (0.69) | HTR2AHTR2CDRD2DRD3HTR2B | |
| SCHEMBL30321010 | 0.90 | HTR2A (0.65) | HTR2AHTR2CDRD2DRD3HTR2B | |
| SCHEMBL25545435 | 0.90 | HTR2A (0.65) | HTR2AHTR2CDRD2DRD3HTR2B | |
| SCHEMBL27580779 | 0.87 | HTR2A (0.75) | HTR2AHTR2CDRD2DRD3HTR2B | |
| SCHEMBL25783413 | 0.86 | HTR2A (0.53) | HTR2AHTR2CDRD2DRD3HTR2B | |
| SCHEMBL11208707 | 0.86 | HSD17B10 (0.72) | HTR2AHTR2CDRD2DRD3HTR2B | |
| Lysergide SCHEMBL28117173 | 0.85 | HTR2A (0.91) | HTR2AHTR2CDRD2DRD3HTR2B | |
| SCHEMBL2469887 | 0.85 | HTR2A (0.80) | HTR2AHTR2CDRD2DRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4155306-A1 | NEUROACTIVE ERGOLINE ANALOGUE | Beckley Psytech Limited (GB) | 2023-03-29 | — | — | EP | disclosed |