SCHEMBL2469887

SCHEMBL2469887

CN(C)C(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 11/20 0.80
▸ HTR1A P08908 4/20 0.80
▸ DRD2 P14416 4/20 0.80
▸ DRD4 P21917 4/20 0.80
▸ DRD5 P21918 4/20 0.80
▸ HTR1D P28221 4/20 0.80
▸ HTR1E P28566 4/20 0.80
▸ HTR7 P34969 4/20 0.80
▸ HRH1 P35367 4/20 0.80
▸ DRD3 P35462 4/20 0.80
▸ HTR2B P41595 4/20 0.80
▸ HTR5A P47898 4/20 0.80
▸ HTR6 P50406 4/20 0.80
▸ ADRB2 P07550 3/20 0.80
▸ ADRB1 P08588 3/20 0.80
▸ HTR2C P28335 2/20 0.80
▸ KDM4E B2RXH2 1/20 0.76
▸ MEN1 O00255 1/20 0.76
▸ USP2 O75604 1/20 0.76
▸ MAPT P10636 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30886877 1.00 HTR2A (0.80) HTR2AHTR1ADRD2DRD4DRD5
SCHEMBL9853854 0.91 HTR2A (0.76) HTR2AHTR1ADRD2DRD4DRD5
SCHEMBL9853852 0.91 HTR2A (0.76) HTR2AHTR1ADRD2DRD4DRD5
SCHEMBL25545441 0.90 HTR2A (0.75) HTR2AHTR1ADRD2DRD4DRD5
SCHEMBL20970957 0.90 HTR2A (0.75) HTR2AHTR1ADRD2DRD4DRD5
Hydrochloric Acid SCHEMBL9853861 0.90 HTR2A (0.75) HTR2AHTR1ADRD2DRD4DRD5
SCHEMBL29556873 0.90 HTR2A (0.75) HTR2AHTR1ADRD2DRD4DRD5
SCHEMBL28377126 0.90 HTR2A (0.77) HTR2AHTR1ADRD2DRD4DRD5
Hydrochloric Acid SCHEMBL32667423 0.89 HTR2A (0.73) HTR2AHTR1ADRD2DRD4DRD5
Lysergide SCHEMBL28202464 0.89 HTR2A (0.96) HTR2AHTR1ADRD2DRD4DRD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2026-04-23 — — US disclosed
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME KULEON LLC (US) 2026-04-02 — — US disclosed
US-20260083759-A1 Combinations Comprising Psychedelics for the Treatment of Schizophrenia and Other Neuropsychiatric and Neurologic Disorders HADASIT MED RES SERVICE (IL) 2026-03-26 — — US disclosed
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-10 — — US disclosed
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-03 — — US disclosed
US-20250376436-A1 Selective Serotonin Receptor Modulators and Methods of Making and Using the Same Park City Bio, LLC (US) 2025-12-11 — — US disclosed
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS KULEON LLC (US) 2025-11-06 — — US disclosed
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same Kuleon, LLC (US) 2025-10-14 — — US disclosed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 — — EP disclosed
US-20250289817-A1 SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2025-09-18 — — US disclosed
WO-2022079574-A1 COMPOSITIONS FOR REDUCING INFLAMMATION TO IMPROVE OR MAINTAIN MENTAL OR PHYSICAL HEALTH GOODCAP PHARMACEUTICALS LTD. (CA) 2022-04-21 — — WO disclosed
US-20210361679-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2021-11-25 — — US disclosed
US-20210346346-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2021-11-11 — — US disclosed
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CAAMTECH, INC. 2019-05-16 — — US disclosed
US-20110257628-A1 INSTRUMENT FOR ALLEVIATING ADDICTIVE DRUG CRAVING, METHOD FOR USING SAME AND METHOD FOR TREATING ADDICTIVE DRUG DEPENDENCE HIRAI SHINJI 2011-10-20 — — US disclosed
EP-2371340-A1 INSTRUMENT FOR ALLEVIATING ADDICTIVE DRUG CRAVING, METHOD FOR USING SAME AND METHOD FOR TREATING ADDICTIVE DRUG DEPENDENCE Hirai, Shinji (JP) 2011-10-05 — — EP disclosed
WO-2007128409-A1 INSECTICIDAL DESPYRROLE ANALOGS OF LISURIDE AND LYSERGAMIDES BAYER CROPSCIENCE AG (DE) 2007-11-15 — — WO disclosed
CN-1059210-C Process for preparing 6-heterocyclic-4-amino-1, 3,4, 5-tetrahydrobenz [ cd ] indoles and their pharmaceutically acceptable acid addition salts LILLY CO ELI (US) 2000-12-06 — — CN disclosed
CN-1268352-A Method for preparing medicinal prepns. contg. 6-heterocycle-4-amino-1,3,4,5-tetrabenzo [cd] indole LILLY CO ELI (US) 2000-10-04 — — CN disclosed
CN-1066072-A 6-heterocyclic-4-amino-1, 3, 4, 5-tetrahydrobenzo [ cd ] indoles LILLY CO ELI (US) 1992-11-11 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CNR1, CNR2, HTR5A HTR2A 6/4885HTR1A 5/4885DRD2 32/4885
US-20250376436-A1 Selective Serotonin Receptor Modulators and Methods of Making and Using the Same HTR1A, HTR4, HTR5A HTR2A 8/4885HTR1A 1/4885DRD2 65/4885
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME HTR2C, HTR7, HTR6 HTR2A 6/4885HTR1A 5/4885DRD2 38/4885
US-20250289817-A1 SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME HTR5A, HTR1A, HTR3A HTR2A 5/4885HTR1A 2/4885DRD2 143/4885
US-20210346346-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND HTR3A, HTR2A, HTR5A HTR2A 2/4885HTR1A 5/4885DRD2 44/4885
US-20260083759-A1 Combinations Comprising Psychedelics for the Treatment of Schizophrenia and Other Neuropsychiatric and Neurologic Disorders BDNF, NTRK2, GRIN2A HTR2A 33/4885HTR1A 34/4885DRD2 32/4885
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same HTR7, HTR2C, HTR1A HTR2A 8/4885HTR1A 3/4885DRD2 50/4885
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND ADRA2C, ADRB3, ADRA2B HTR2A 19/4885HTR1A 22/4885DRD2 60/4885
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS HTR2A, HTR2C, HTR3A HTR2A 1/4885HTR1A 4/4885DRD2 55/4885
US-20210361679-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND HTR3A, HTR2A, HTR5A HTR2A 2/4885HTR1A 5/4885DRD2 44/4885
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same HTR1D, HTR1A, HTR4 HTR2A 14/4885HTR1A 2/4885DRD2 51/4885
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same HTR5A, HTR1A, HTR1D HTR2A 16/4885HTR1A 2/4885DRD2 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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