Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 19/20 | 0.72 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20254571 | 1.00 | RIPK1 (0.72) | RIPK1PDE5A | |
| SCHEMBL20254431 | 0.89 | RIPK1 (0.70) | RIPK1 | |
| SCHEMBL20254439 | 0.88 | RIPK1 (0.77) | RIPK1 | |
| SCHEMBL20254493 | 0.86 | RIPK1 (0.59) | RIPK1 | |
| SCHEMBL20254437 | 0.86 | RIPK1 (0.56) | RIPK1 | |
| SCHEMBL20254430 | 0.85 | RIPK1 (0.65) | RIPK1 | |
| SCHEMBL18248420 | 0.84 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL18255208 | 0.84 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL20254445 | 0.84 | RIPK1 (0.64) | RIPK1 | |
| SCHEMBL24018697 | 0.82 | RIPK1 (0.71) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110383066-B | Compounds, compositions and methods | 戴纳立制药公司 | 2023-03-31 | — | — | CN | disclosed |