Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.63 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469159 | 0.91 | GRM5 (0.67) | GRM5SMYD3KDM4EGAAKMT2A | |
| SCHEMBL29580741 | 0.88 | GRM5 (0.66) | GRM5SMYD3KDM4EGAAKMT2A | |
| SCHEMBL2241357 | 0.83 | GRM5 (0.77) | GRM5SMYD3KDM4EGAAKMT2A | |
| SCHEMBL29421288 | 0.82 | P2RX7 (0.49) | RAB9ACNR2NAMPT | |
| SCHEMBL16394406 | 0.80 | GRM5 (0.88) | GRM5SMYD3KDM4EGAAKMT2A | |
| SCHEMBL2246381 | 0.80 | GRM5 (0.82) | GRM5SMYD3KDM4EGAAKMT2A | |
| SCHEMBL21722438 | 0.80 | SMYD3 (0.55) | GRM5SMYD3KDM4EGAAKMT2A | |
| SCHEMBL2590689 | 0.79 | GRM5 (0.80) | GRM5SMYD3KDM4EGAAKMT2A | |
| SCHEMBL22449377 | 0.79 | GRM5 (0.80) | GRM5SMYD3KDM4EGAAKMT2A | |
| SCHEMBL24296470 | 0.78 | CNR2 (0.53) | SMYD3RAB9ACNR2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520127-B | Piperidinyl-substituted and piperazinyl-substituted heteroaromatic carboxamides as modulators of GPR6 | 武田药品工业株式会社 | 2023-05-16 | — | — | CN | claimed |
| CN-116867783-A | Pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-10-10 | — | — | CN | disclosed |