Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 5/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30323356 | 0.84 | TLR7 (0.43) | AURKAAURKBJAK2JAK1TYK2 | |
| SCHEMBL30323324 | 0.84 | TLR7 (0.43) | AURKAAURKBJAK2JAK1TYK2 | |
| SCHEMBL30323327 | 0.83 | JAK2 (0.38) | AURKAJAK2JAK1TYK2JAK3 | |
| SCHEMBL22571385 | 0.81 | RXFP1 (0.43) | AURKAAURKBJAK2JAK1TYK2 | |
| SCHEMBL23388918 | 0.78 | TLR7 (0.41) | AURKAAURKBJAK2JAK1TYK2 | |
| SCHEMBL30323407 | 0.78 | JAK2 (0.37) | AURKAAURKBJAK2JAK1TYK2 | |
| SCHEMBL30323335 | 0.77 | JAK2 (0.37) | JAK2JAK1TYK2JAK3NR3C1 | |
| SCHEMBL29888201 | 0.76 | RXFP1 (0.42) | AURKAAURKBAKR1C3MEN1KMT2A | |
| SCHEMBL23388810 | 0.76 | RXFP1 (0.42) | AURKAAURKBAKR1C3MEN1KMT2A | |
| SCHEMBL30323394 | 0.76 | AURKA (0.47) | AURKAAURKBJAK2JAK3AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023049199-A1 | AZOLE COMPOUNDS | ZENO MANAGEMENT, INC. (US) | 2023-03-30 | — | — | WO | disclosed |