Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30323324 | 1.00 | TLR7 (0.43) | TLR7JAK2JAK1TYK2JAK3 | |
| SCHEMBL23388918 | 0.87 | TLR7 (0.41) | TLR7JAK2JAK1TYK2JAK3 | |
| SCHEMBL22571385 | 0.87 | RXFP1 (0.43) | JAK2JAK1TYK2JAK3AURKA | |
| SCHEMBL23423434 | 0.85 | LMNA (0.46) | JAK2JAK1TYK2JAK3TRPV1 | |
| SCHEMBL30323387 | 0.84 | AURKA (0.37) | JAK2JAK1TYK2JAK3AURKA | |
| SCHEMBL23388810 | 0.81 | RXFP1 (0.42) | AURKAAURKBRXFP1 | |
| SCHEMBL29888201 | 0.81 | RXFP1 (0.42) | AURKAAURKBRXFP1 | |
| SCHEMBL23423242 | 0.80 | LMNA (0.45) | JAK2JAK1TYK2JAK3TRPV1 | |
| SCHEMBL30323327 | 0.79 | JAK2 (0.38) | TLR7JAK2JAK1TYK2JAK3 | |
| SCHEMBL30323407 | 0.79 | JAK2 (0.37) | JAK2JAK1TYK2JAK3AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023049199-A1 | AZOLE COMPOUNDS | ZENO MANAGEMENT, INC. (US) | 2023-03-30 | — | — | WO | disclosed |