SCHEMBL30324901

SCHEMBL30324901

Cc1ccc(S(=O)(=O)n2ccc3c(-c4cc([N+](=O)[O-])ccc4F)cn(C)c(=O)c32)cc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 10/20 0.52
▸ HTR6 P50406 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ LMNA P02545 2/20 0.35
▸ CASP1 P29466 1/20 0.34
▸ CASP3 P42574 1/20 0.34
▸ CASP4 P49662 1/20 0.34
▸ CASP7 P55210 1/20 0.34
▸ CASP9 P55211 1/20 0.34
▸ CASP6 P55212 1/20 0.34
▸ MAPT P10636 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ PARL Q9H300 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15069163 1.00 BRD4 (0.52) BRD4HTR6L3MBTL1LMNACASP1
SCHEMBL15069625 0.90 BRD4 (0.49) BRD4HTR6L3MBTL1LMNAMAPT
SCHEMBL31073711 0.86 BRD4 (0.54) BRD4
SCHEMBL15069411 0.86 BRD4 (0.55) BRD4
SCHEMBL31395498 0.86 BRD4 (0.55) BRD4
SCHEMBL15069178 0.86 BRD4 (0.52) BRD4HTR6L3MBTL1LMNAMAPT
SCHEMBL31073867 0.86 BRD4 (0.49) BRD4HTR6LMNAMAPTMEN1
SCHEMBL20384519 0.84 BRD4 (0.56) BRD4
SCHEMBL15069384 0.84 BRD4 (0.54) BRD4
SCHEMBL31469056 0.83 BRD4 (0.61) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702022-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE Halda Therapeutics Opco, Inc. (US) 2026-03-04 — — EP disclosed
US-20250388605-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO INC (US) 2025-12-25 — — US disclosed
CN-119684283-A Pyrrolo [2,3-c ] pyridines and use thereof 山东新时代药业有限公司 2025-03-25 — — CN disclosed
WO-2024211684-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. (US) 2024-10-10 — — WO disclosed
WO-2024193527-A1 PYRROLO[2,3-C]PYRIDINE COMPOUND AS BROMODOMAIN INHIBITOR 山东新时代药业有限公司 2024-09-26 — — WO disclosed
WO-2024054955-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. (US) 2024-03-14 — — WO disclosed
WO-2024054956-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. (US) 2024-03-14 — — WO disclosed
WO-2023059581-A1 HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. (US) 2023-04-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388605-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE BRD4, BRDT, BICRA BRD4 1/4885HTR6 1278/4885L3MBTL1 1370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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