Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.55 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069411 | 1.00 | BRD4 (0.55) | BRD4TRIM24BRD2BRD3BRDT | |
| SCHEMBL20384519 | 0.92 | BRD4 (0.56) | BRD4TRIM24BRD2BRD3BRDT | |
| SCHEMBL15069384 | 0.90 | BRD4 (0.54) | BRD4 | |
| SCHEMBL20384274 | 0.88 | BRD4 (0.54) | BRD4 | |
| SCHEMBL15069587 | 0.88 | BRD4 (0.56) | BRD4 | |
| SCHEMBL20384392 | 0.87 | BRD4 (0.54) | BRD4 | |
| SCHEMBL15069163 | 0.86 | BRD4 (0.52) | BRD4 | |
| SCHEMBL30324901 | 0.86 | BRD4 (0.52) | BRD4 | |
| SCHEMBL20384194 | 0.86 | BRD4 (0.54) | BRD4 | |
| SCHEMBL15069458 | 0.85 | BRD4 (0.62) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739307-A2 | TARGETED EPIGENETIC THERAPIES FOR DISORDERS OF PROGRANULIN DEFICIENCY | The General Hospital Corporation (US) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025010291-A2 | TARGETED EPIGENETIC THERAPIES FOR DISORDERS OF PROGRANULIN DEFICIENCY | THE GENERAL HOSPITAL CORPORATION (US) | 2025-01-09 | — | — | WO | disclosed |