Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | SORD | Q00796 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2038871 | 0.84 | KMT2A (0.38) | RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31366256 | 0.84 | KMT2A (0.38) | RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22256745 | 0.82 | NPC1 (0.40) | RAB9ANPC1KMT2APOLBHSD17B10 | |
| SCHEMBL20517447 | 0.79 | NPC1 (0.41) | RAB9ANPC1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL20517639 | 0.79 | ALDH1A1 (0.36) | RAB9ANPC1KMT2ASMN1; SMN2POLB | |
| SCHEMBL18420384 | 0.79 | CYP4F2 (0.39) | RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30600776 | 0.79 | ALDH1A1 (0.36) | RAB9ANPC1KMT2ASMN1; SMN2POLB | |
| SCHEMBL30600870 | 0.79 | NPC1 (0.41) | RAB9ANPC1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL30326198 | 0.79 | CYP4F2 (0.39) | RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18179064 | 0.79 | SMN1; SMN2 (0.40) | RAB9ASMN1; SMN2POLBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049275-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2025043148-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2025-02-27 | — | — | WO | disclosed |
| CN-115989224-B | Plasma kallikrein inhibitors | 默沙东有限责任公司 | 2025-02-25 | — | — | CN | disclosed |
| EP-4164634-A1 | PLASMA KALLIKREIN INHIBITORS | Merck Sharp & Dohme LLC (US) | 2023-04-19 | — | — | EP | disclosed |
| CN-115989224-A | Plasma kallikrein inhibitors | 默沙东有限责任公司 | 2023-04-18 | — | — | CN | disclosed |