Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.43 |
| ▸ | FEN1 | P39748 | 6/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31213932 | 0.80 | FGFR1 (0.66) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31213871 | 0.80 | FGFR1 (0.58) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31213998 | 0.78 | FGFR1 (0.53) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL25715485 | 0.78 | CYP2C9 (0.45) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31214014 | 0.78 | CYP3A4 (0.61) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31213876 | 0.77 | FGFR1 (0.60) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL25715486 | 0.77 | FGFR1 (0.44) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL25715484 | 0.77 | ALOX5AP (0.46) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31213957 | 0.76 | CYP3A4 (0.59) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31213902 | 0.76 | FGFR1 (0.59) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383905-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | 3H PHARMACEUTICALS CO., LTD. (CN) | 2024-11-21 | — | — | US | disclosed |
| EP-4405358-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | 3H Pharmaceuticals Co., Ltd. (CN) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023046117-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | 3H PHARMACEUTICALS CO., LTD. (CN) | 2023-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383905-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | FGFR1, FGFR3, FGFR4 | CYP3A4 594/4885CYP2D6 638/4885FGFR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.