Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.46 |
| ▸ | FEN1 | P39748 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 4/20 | 0.40 |
| ▸ | ACVRL1 | P37023 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715608 | 0.85 | TNK2 (0.39) | ALOX5APFEN1TNK2ACVRL1 | |
| SCHEMBL25715485 | 0.83 | CYP2C9 (0.45) | ALOX5APFEN1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL25715486 | 0.82 | FGFR1 (0.44) | ALOX5APFEN1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL30326192 | 0.77 | CYP3A4 (0.48) | ALOX5APFEN1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL25715553 | 0.74 | CYP11B1 (0.45) | CYP2C9CYP3A4CYP2D6CYP2C19TNK2 | |
| SCHEMBL28981128 | 0.74 | ALOX5AP (0.54) | ALOX5APFEN1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL25715487 | 0.74 | FGFR1 (0.52) | ALOX5APFEN1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL25718337 | 0.74 | FGFR1 (0.65) | ALOX5APFEN1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL29407664 | 0.74 | CYP3A4 (0.56) | ALOX5APFEN1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL26106772 | 0.74 | CYP3A4 (0.56) | ALOX5APFEN1CYP2C9CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |