Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16274725 | 0.98 | EGLN2 (0.42) | EGLN2FTOKDM4EKCNA5NPC1 | |
| SCHEMBL29586409 | 0.98 | EGLN2 (0.42) | EGLN2FTOKDM4EKCNA5NPC1 | |
| Lithium SCHEMBL30327463 | 0.96 | EGLN2 (0.41) | EGLN2FTOKDM4EKCNA5NPC1 | |
| SCHEMBL16274573 | 0.96 | EGLN2 (0.41) | EGLN2FTOKDM4EKCNA5NPC1 | |
| SCHEMBL28105075 | 0.83 | PDE5A (0.40) | EGLN2FTOKDM4EKCNA5NPC1 | |
| SCHEMBL12604118 | 0.79 | KCNA5 (0.43) | KDM4EKCNA5ALDH1A1NPSR1CA2 | |
| Lithium Ion SCHEMBL29455178 | 0.79 | KCNA5 (0.40) | KDM4EKCNA5ALDH1A1NPSR1CA2 | |
| Lithium Ion SCHEMBL16274572 | 0.79 | KCNA5 (0.40) | KDM4EKCNA5ALDH1A1NPSR1CA2 | |
| SCHEMBL14020797 | 0.78 | KCNA5 (0.44) | KDM4EKCNA5ALDH1A1NPSR1CA2 | |
| SCHEMBL14020800 | 0.78 | POLB (0.44) | KDM4EKCNA5ALDH1A1NPSR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096124-A | Organic light emitting diode, display device including the same, and illumination device including the same | 诺瓦尔德股份有限公司 | 2023-05-09 | — | — | CN | disclosed |