Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | ATR | Q13535 | 6/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30327601 | 0.93 | RXRA (0.39) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL30327596 | 0.90 | RXRA (0.51) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL25247927 | 0.90 | RXRA (0.51) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL25247427 | 0.87 | RXRA (0.46) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL29410331 | 0.87 | RXRA (0.46) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL25291287 | 0.87 | RXRA (0.46) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL31261983 | 0.83 | KDM4E (0.43) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL18399275 | 0.83 | RXRA (0.48) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL14816270 | 0.81 | RXRA (0.59) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL14816269 | 0.81 | RXRA (0.59) | RXRARXRBRXRGALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096712-A | Novel compounds | NRG治疗有限公司 | 2023-05-09 | — | — | CN | disclosed |