Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30327910 | 0.99 | PIM1 (0.40) | PIM1PIM3PIM2HCRTR1HCRTR2 | |
| SCHEMBL30327874 | 0.86 | PIM1 (0.42) | PIM1PIM3PIM2HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL30327990 | 0.85 | PIM1 (0.41) | PIM1PIM3PIM2HCRTR1HCRTR2 | |
| SCHEMBL30328097 | 0.80 | PHGDH (0.39) | PIM1PIM3PIM2ALDH1A1HPGD | |
| SCHEMBL30328564 | 0.80 | PIM1 (0.40) | PIM1PIM3PIM2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL30329091 | 0.79 | PHGDH (0.38) | PIM1PIM3PIM2ALDH1A1HPGD | |
| SCHEMBL20469181 | 0.77 | MCHR1 (0.45) | PIM1PIM3PIM2ALDH1A1HPGD | |
| SCHEMBL13741399 | 0.76 | ADRB2 (0.48) | HCRTR1HCRTR2CYP1A2DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL30328028 | 0.76 | OGA (0.40) | PIM1PIM3PIM2ALDH1A1HPGD | |
| SCHEMBL20468834 | 0.75 | TSHR (0.44) | PIM1PIM3PIM2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |