Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 10/20 | 0.37 |
| ▸ | ACACB | O00763 | 6/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30329266 | 0.80 | OPRL1 (0.41) | ACACAACACBGRM5OPRL1OPRM1 | |
| SCHEMBL30327913 | 0.79 | ACACB (0.42) | ACACAACACB | |
| Hydrochloric Acid SCHEMBL30328975 | 0.77 | TYK2 (0.41) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL30328553 | 0.76 | PIM1 (0.36) | JAK2JAK1TYK2JAK3TSHR | |
| Hydrochloric Acid SCHEMBL30328124 | 0.74 | OPRL1 (0.47) | OPRL1OPRM1 | |
| SCHEMBL25164772 | 0.72 | CYP11B1 (0.32) | ACACAACACB | |
| SCHEMBL30329301 | 0.71 | OPRL1 (0.45) | ACACAACACBGRM5OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL30328583 | 0.70 | TSHR (0.39) | OPRL1OPRM1TSHR | |
| Hydrochloric Acid SCHEMBL30329056 | 0.70 | OPRL1 (0.44) | ACACAACACBGRM5OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL30327686 | 0.70 | GRM5 (0.46) | ACACAACACBGRM5OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |