Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 5/20 | 0.45 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30328552 | 0.92 | CYP11B2 (0.50) | CYP11B2ACACBEIF2AK4SPRHDAC2 | |
| SCHEMBL30329023 | 0.89 | CYP11B2 (0.49) | CYP11B2ACACBEIF2AK4SCD5SPR | |
| SCHEMBL30329297 | 0.86 | CYP11B2 (0.47) | CYP11B2ACACBEIF2AK4SCD5SPR | |
| SCHEMBL30328647 | 0.86 | CYP11B2 (0.50) | CYP11B2ACACBEIF2AK4SCD5SPR | |
| SCHEMBL25163972 | 0.84 | CYP11B2 (0.49) | CYP11B2ACACBEIF2AK4SCD5SPR | |
| SCHEMBL30329015 | 0.83 | CYP11B2 (0.49) | CYP11B2ACACBEIF2AK4SCD5SPR | |
| SCHEMBL30328268 | 0.81 | CYP11B2 (0.49) | CYP11B2ACACBEIF2AK4HDAC2HDAC1 | |
| SCHEMBL30328924 | 0.81 | CYP11B2 (0.49) | CYP11B2ACACBEIF2AK4SCD5HDAC2 | |
| SCHEMBL30328058 | 0.80 | EIF2AK4 (0.53) | CYP11B2ACACBEIF2AK4SCD5RORC | |
| SCHEMBL30327774 | 0.80 | CYP11B2 (0.48) | CYP11B2ACACBEIF2AK4HDAC2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |