Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 16/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 11/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25164791 | 1.00 | HCRTR2 (0.44) | HCRTR2HCRTR1EGLN1PTPN11 | |
| SCHEMBL25164543 | 0.93 | HCRTR2 (0.41) | HCRTR2HCRTR1EGLN1 | |
| SCHEMBL30328538 | 0.93 | HCRTR2 (0.41) | HCRTR2HCRTR1EGLN1 | |
| SCHEMBL30328218 | 0.89 | PTPN11 (0.43) | HCRTR2HCRTR1PTPN11 | |
| SCHEMBL25164431 | 0.89 | PTPN11 (0.43) | HCRTR2HCRTR1PTPN11 | |
| SCHEMBL25163917 | 0.86 | ACACA (0.38) | HCRTR2HCRTR1PTPN11 | |
| SCHEMBL30327966 | 0.86 | ACACA (0.38) | HCRTR2HCRTR1PTPN11 | |
| SCHEMBL30329242 | 0.86 | HCRTR2 (0.39) | HCRTR2HCRTR1 | |
| SCHEMBL25163649 | 0.86 | HCRTR2 (0.39) | HCRTR2HCRTR1 | |
| SCHEMBL25164754 | 0.85 | HCRTR2 (0.41) | HCRTR2HCRTR1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |