Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.58 |
| ▸ | EGFR | P00533 | 2/20 | 0.55 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.55 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.55 |
| ▸ | KIT | P10721 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | TEK | Q02763 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30415972 | 1.00 | BTK (0.58) | BTKEGFRNUDT14NUDT5KIT | |
| SCHEMBL24192714 | 1.00 | BTK (0.58) | BTKEGFRNUDT14NUDT5KIT | |
| SCHEMBL24196616 | 0.99 | BTK (0.58) | BTKEGFRNUDT14NUDT5KIT | |
| SCHEMBL24196863 | 0.99 | BTK (0.57) | BTKEGFRNUDT14NUDT5KIT | |
| SCHEMBL24196614 | 0.95 | BTK (0.57) | BTKEGFRNUDT14NUDT5KIT | |
| SCHEMBL30416245 | 0.95 | BTK (0.57) | BTKEGFRNUDT14NUDT5KIT | |
| SCHEMBL24196860 | 0.93 | BTK (0.60) | BTKEGFRNUDT14NUDT5KIT | |
| SCHEMBL24197118 | 0.92 | EGFR (0.63) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL24196640 | 0.92 | BTK (0.57) | BTKEGFRNUDT14NUDT5KIT | |
| SCHEMBL24196848 | 0.91 | EGFR (0.62) | BTKEGFRNUDT14NUDT5LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180432-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |