Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | LCK | P06239 | 4/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | TEK | Q02763 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.55 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.55 |
| ▸ | ITK | Q08881 | 1/20 | 0.55 |
| ▸ | KIT | P10721 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | LYN | P07948 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24196614 | 1.00 | BTK (0.57) | BTKEGFRLCKSRCTEK | |
| SCHEMBL24196860 | 0.97 | BTK (0.60) | BTKEGFRLCKNUDT14NUDT5 | |
| SCHEMBL24196616 | 0.96 | BTK (0.58) | BTKEGFRLCKSRCTEK | |
| SCHEMBL30331087 | 0.95 | BTK (0.58) | BTKEGFRLCKSRCTEK | |
| SCHEMBL30415972 | 0.95 | BTK (0.58) | BTKEGFRLCKSRCTEK | |
| SCHEMBL24192714 | 0.95 | BTK (0.58) | BTKEGFRLCKSRCTEK | |
| SCHEMBL24196863 | 0.94 | BTK (0.57) | BTKEGFRLCKSRCTEK | |
| SCHEMBL30416097 | 0.92 | EGFR (0.59) | BTKEGFRLCKSRCTEK | |
| SCHEMBL24197324 | 0.92 | EGFR (0.59) | BTKEGFRLCKSRCTEK | |
| SCHEMBL24196637 | 0.91 | ERBB3 (0.58) | BTKEGFRLCKSRCTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134028-A | Compound capable of degrading BTK kinase, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2023-05-16 | — | — | CN | disclosed |