Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14373155 | 0.83 | DYRK3 (0.48) | FYNMKNK1 | |
| SCHEMBL3033593 | 0.83 | FYN (0.88) | FYN | |
| SCHEMBL477064 | 0.81 | DYRK1A (0.70) | FYNMKNK1 | |
| SCHEMBL3037756 | 0.81 | FYN (0.61) | FYNMKNK1 | |
| SCHEMBL18613682 | 0.78 | FYN (1.00) | FYN | |
| SCHEMBL3038110 | 0.78 | FYN (0.65) | FYNMKNK1 | |
| SCHEMBL3038068 | 0.78 | FYN (0.72) | FYNMKNK1 | |
| SCHEMBL18613433 | 0.78 | FYN (1.00) | FYN | |
| SCHEMBL14373191 | 0.78 | FYN (0.60) | FYNMKNK1 | |
| SCHEMBL3033429 | 0.76 | MKNK1 (1.00) | FYNMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216798-A1 | FUSED HETEROCYCLES AS LCK INHIBITORS | ASTELLAS PHARMA INC (JP) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216798-A1 | FUSED HETEROCYCLES AS LCK INHIBITORS | LCK, ZAP70, FYN | FYN 3/4885MKNK1 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.