Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31029604 | 1.00 | KIT (0.49) | KITMAP4K4MAPTALDH1A1LMNA | |
| SCHEMBL29697503 | 0.91 | KIT (0.49) | KITMAP4K4MAPTALDH1A1LMNA | |
| SCHEMBL21786285 | 0.87 | KIT (0.48) | KITMAP4K4MAPTALDH1A1LMNA | |
| SCHEMBL19616882 | 0.79 | KIT (0.48) | KITMAP4K4MAPTALDH1A1LMNA | |
| SCHEMBL30311594 | 0.79 | RET (0.49) | KITGPR119 | |
| SCHEMBL21243934 | 0.79 | KIT (0.48) | KITMAP4K4MAPTALDH1A1LMNA | |
| SCHEMBL2572791 | 0.78 | AKT1 (0.50) | KITMAP4K4MAPTALDH1A1LMNA | |
| SCHEMBL22307571 | 0.78 | AKT1 (0.54) | KITMAP4K4MAPTALDH1A1LMNA | |
| SCHEMBL2796064 | 0.78 | KIT (0.49) | KITMAP4K4CNR1CNR2CKS1B | |
| SCHEMBL21591691 | 0.77 | KIT (0.44) | KITMAP4K4MAPTCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023045960-A1 | PYRIDINE DERIVATIVE AND USE THEREOF | 四川汇宇制药股份有限公司 | 2023-03-30 | — | — | WO | disclosed |