⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1854290 | 0.68 | — | — | |
| SCHEMBL6860487 | 0.58 | — | — | |
| SCHEMBL467461 | 0.54 | — | — | |
| SCHEMBL17137826 | 0.53 | — | — | |
| Water SCHEMBL21439849 | 0.53 | — | — | |
| Bromide SCHEMBL2338080 | 0.53 | — | — | |
| SCHEMBL4302333 | 0.53 | — | — | |
| Water SCHEMBL21439848 | 0.53 | KDM4A (0.36) | — | |
| SCHEMBL31118006 | 0.51 | — | — | |
| SCHEMBL818 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1031 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160517-B1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE LYON (FR) | 2024-06-12 | — | — | EP | claimed |
| US-20240158414-A1 | BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH, INC. | 2024-05-16 | — | — | US | claimed |
| WO-2024035950-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | claimed |
| WO-2024029877-A1 | NOVEL PURINE DERIVATIVE COMPOUNDS AS A3 ADENOSINE RECEPTOR AGONISTS | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | claimed |
| EP-4041714-B1 | BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH INC (US) | 2023-12-13 | — | — | EP | claimed |
| EP-3555112-B1 | FLUOROGENIC GLYCOSIDASE SUBSTRATE AND ASSOCIATED DETECTION METHOD | ECOLE NORMALE SUPERIEURE LYON (FR) | 2023-12-06 | — | — | EP | claimed |
| CN-109983012-B | Ketone inhibitors of lysine gum protease | 莱特豪斯制药公司 | 2023-12-01 | — | — | CN | claimed |
| CN-110088089-B | Benzyl amino pyridyl cyclopropane carboxylic acid, pharmaceutical composition and application thereof | 勃林格殷格翰国际有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-110177773-B | Benzyl aminopyridine cyclopropanecarboxylic acid, pharmaceutical composition and application thereof | 勃林格殷格翰国际有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-110248929-B | Benzyl amino pyrazinyl cyclopropanecarboxylic acid, pharmaceutical composition and use thereof | 勃林格殷格翰国际有限公司 | 2023-05-12 | — | — | CN | claimed |
| WO-1993014069-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF AND ANGIOTENSIN II | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-07-22 | — | — | WO | claimed |
| EP-0539421-A1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-05-05 | — | — | EP | claimed |
| EP-0234356-B1 | PHOSPHORIC-ACID ESTERS | BAYER AG (DE) | 1989-07-26 | — | — | EP | claimed |
| EP-0234356-A1 | Phosphoric-acid esters | BAYER AG (DE) | 1987-09-02 | — | — | EP | claimed |
| US-4689321-A | CYTOLYSIS, ANTITUMOR, ANTICARCINOGENIC | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1987-08-25 | — | — | US | claimed |
| EP-0222598-A2 | Dihydropyridine anti-ischaemic and antihypertensive agents | Pfizer Limited (GB) | 1987-05-20 | — | — | EP | claimed |
| US-4661485-A | 2-pyrimidylaminoalkoxymethyl-6-methyl-3,5-bis (alkoxycarbony-1)-1,4-dihydropyridine antihypertensive agents | PFIZER INC. (US) | 1987-04-28 | — | — | US | claimed |
| EP-0139917-A1 | Pharmaceutical preparations, acylated hydrazine derivatives, methods for their preparation | CIBA-GEIGY AG (CH) | 1985-05-08 | — | — | EP | claimed |
| US-4172197-A | BACTERICIDES | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1979-10-23 | — | — | US | claimed |
| US-4091211-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1978-05-23 | — | — | US | claimed |