SCHEMBL6860487

SCHEMBL6860487

O=c1ncn[c][nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL303343 0.58
SCHEMBL2205724 0.53
SCHEMBL2927541 0.49
SCHEMBL3477835 0.46
SCHEMBL442086 0.41
SCHEMBL14932121 0.40
SCHEMBL654468 0.38
SCHEMBL722089 0.35
SCHEMBL6851025 0.32 GSK3B (0.44)
SCHEMBL10426602 0.32

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4091211-A ANTIBIOTICS HOFFMANN-LA ROCHE INC. (US) 1978-05-23 US claimed
CN-117224541-A Treatment of obesity 北京强新生物科技有限公司 2023-12-15 CN disclosed
CN-112955143-B Treatment of non-alcoholic fatty liver disease 北京强新生物科技有限公司 2023-10-13 CN disclosed
CN-112996507-B Treatment of obesity 北京强新生物科技有限公司 2023-09-05 CN disclosed
EP-0979103-B1 LIGHT IMAGING CONTRAST AGENTS AMERSHAM HEALTH AS (NO) 2004-01-02 EP disclosed
US-6350431-B1 LIGHT IMAGE CONTRAST AGENT WITH CHROMOPORES LINKED WITH POLYETHER NYCOMED IMAGING AS (NO) 2002-02-26 US disclosed
EP-0979103-A1 COMPOUNDS NYCOMED IMAGING AS (NO) 2000-02-16 EP disclosed
WO-1998048838-A1 COMPOUNDS NYCOMED IMAGING AS (NO) 1998-11-05 WO disclosed
US-4348518-A Cephalosporins HOFFMANN-LA ROCHE INC. (US) 1982-09-07 US disclosed
US-4091211-A ANTIBIOTICS HOFFMANN-LA ROCHE INC. (US) 1978-05-23 US disclosed