Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25526439 | 1.00 | HPRT1 (0.44) | HPRT1ITGB1ITGA4CTSGCMA1 | |
| SCHEMBL25526187 | 1.00 | HPRT1 (0.44) | HPRT1ITGB1ITGA4CTSGCMA1 | |
| SCHEMBL25526450 | 1.00 | HPRT1 (0.44) | HPRT1ITGB1ITGA4CTSGCMA1 | |
| SCHEMBL25526176 | 1.00 | HPRT1 (0.44) | HPRT1ITGB1ITGA4CTSGCMA1 | |
| SCHEMBL25526186 | 1.00 | HPRT1 (0.44) | HPRT1ITGB1ITGA4CTSGCMA1 | |
| SCHEMBL25526383 | 1.00 | HPRT1 (0.44) | HPRT1ITGB1ITGA4CTSGCMA1 | |
| SCHEMBL25526173 | 1.00 | HPRT1 (0.44) | HPRT1ITGB1ITGA4CTSGCMA1 | |
| SCHEMBL25526195 | 1.00 | HPRT1 (0.44) | HPRT1ITGB1ITGA4CTSGCMA1 | |
| SCHEMBL25526058 | 1.00 | HPRT1 (0.44) | HPRT1ITGB1ITGA4CTSGCMA1 | |
| SCHEMBL25526042 | 0.99 | HPRT1 (0.45) | HPRT1ITGB1ITGA4CTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151049-A1 | Compounds Useful in HIV Therapy | VIIV HEALTHCARE COMPANY (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151049-A1 | Compounds Useful in HIV Therapy | CCR5, CD4, NPC1 | HPRT1 15/4885ITGB1 1713/4885ITGA4 2033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.