SCHEMBL303353

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL304106	0.90	MEN1 (0.43)	LMNAMEN1KMT2APOLBOXTR
	SCHEMBL3378381	0.89	MEN1 (0.42)	LMNAHTTMEN1KMT2APOLB
	SCHEMBL3378801	0.87	PIK3CG (0.43)	LMNAMEN1KMT2APOLBPSEN1
	SCHEMBL2211492	0.87	MEN1 (0.53)	LMNAMEN1KMT2APOLBNR1H2
	SCHEMBL2214352	0.87	KDM4E (0.42)	LMNAHTTKDM4EMEN1KMT2A
	SCHEMBL303633	0.86	MEN1 (0.47)	KDM4EMEN1KMT2APSEN1PSEN2
	SCHEMBL303898	0.86	MEN1 (0.49)	KDM4EMEN1KMT2APSEN1PSEN2
	SCHEMBL302166	0.86	MEN1 (0.44)	KDM4EMEN1KMT2APSEN1PSEN2
	SCHEMBL303432	0.85	LMNA (0.42)	LMNAHTTKDM4EMEN1KMT2A
	SCHEMBL18487091	0.85	LMNA (0.45)	LMNAHTTMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.