Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 18/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28471282 | 1.00 | CD274 (0.49) | CD274PDCD1MAOAMAOB | |
| SCHEMBL18728442 | 0.93 | CD274 (0.51) | CD274PDCD1 | |
| SCHEMBL23078186 | 0.91 | PDCD1 (0.44) | CD274PDCD1 | |
| SCHEMBL23078357 | 0.88 | PDCD1 (0.44) | CD274PDCD1 | |
| SCHEMBL21357311 | 0.87 | CD274 (0.46) | CD274PDCD1 | |
| SCHEMBL30335521 | 0.87 | CD274 (0.46) | CD274PDCD1 | |
| SCHEMBL23078807 | 0.87 | PDCD1 (0.42) | CD274PDCD1MAOAMAOB | |
| SCHEMBL20721107 | 0.85 | CD274 (0.65) | CD274PDCD1 | |
| SCHEMBL22757792 | 0.84 | CD274 (0.52) | CD274PDCD1 | |
| SCHEMBL18728986 | 0.84 | CD274 (0.48) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111788193-B | PD-1/PD-L1 small molecule inhibitor and application thereof in medicines | 广东东阳光药业有限公司 | 2023-04-04 | — | — | CN | disclosed |