Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 15/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 15/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23078357 | 0.91 | PDCD1 (0.44) | PDCD1CD274 | |
| SCHEMBL23078654 | 0.90 | PDCD1 (0.43) | PDCD1CD274MRGPRX4 | |
| SCHEMBL23078186 | 0.88 | PDCD1 (0.44) | PDCD1CD274 | |
| SCHEMBL23078657 | 0.87 | PDCD1 (0.44) | PDCD1CD274MRGPRX4 | |
| SCHEMBL28471282 | 0.87 | CD274 (0.49) | PDCD1CD274MAOAMAOB | |
| SCHEMBL30335528 | 0.87 | CD274 (0.49) | PDCD1CD274MAOAMAOB | |
| SCHEMBL23078435 | 0.86 | ERN1 (0.43) | PDCD1CD274ERN1MRGPRX4 | |
| SCHEMBL23078761 | 0.84 | CD274 (0.50) | PDCD1CD274MRGPRX4 | |
| SCHEMBL23078659 | 0.84 | PDCD1 (0.41) | PDCD1CD274 | |
| SCHEMBL23078523 | 0.82 | PDCD1 (0.53) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043116-A1 | BIPHENYL COMPOUNDS, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国药科大学 | 2021-03-11 | — | — | WO | disclosed |