Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 15/20 | 0.68 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.59 |
| ▸ | MET | P08581 | 1/20 | 0.55 |
| ▸ | AXL | P30530 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 4/20 | 0.54 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | TEK | Q02763 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28972312 | 1.00 | FLT3 (0.68) | FLT3RIPK1METAXLKDR | |
| SCHEMBL30336210 | 0.92 | FLT3 (0.72) | FLT3METAXL | |
| SCHEMBL28972505 | 0.92 | FLT3 (0.72) | FLT3METAXL | |
| SCHEMBL30336362 | 0.90 | FLT3 (0.70) | FLT3METAXLKDRKIT | |
| SCHEMBL28972507 | 0.90 | FLT3 (0.70) | FLT3METAXLKDRKIT | |
| SCHEMBL30336351 | 0.89 | FLT3 (0.71) | FLT3METAXLKDR | |
| SCHEMBL28972355 | 0.89 | FLT3 (0.71) | FLT3METAXLKDR | |
| SCHEMBL30336053 | 0.87 | FLT3 (0.72) | FLT3METAXL | |
| SCHEMBL30336593 | 0.87 | FLT3 (0.72) | FLT3METAXL | |
| SCHEMBL28972307 | 0.87 | FLT3 (0.74) | FLT3METAXLKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111646995-B | 4-amino-pyrimidoazenitrogen heterocycle-phenylurea derivative and preparation method and application thereof | 四川大学 | 2023-03-21 | — | — | CN | disclosed |