Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25282013 | 1.00 | MEN1 (0.58) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL30615662 | 0.84 | MEN1 (0.55) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL21463676 | 0.84 | MEN1 (0.55) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL23997395 | 0.80 | MEN1 (0.59) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL30336707 | 0.80 | MEN1 (0.59) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL28357637 | 0.78 | MEN1 (0.51) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL28492451 | 0.77 | MEN1 (0.56) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL31362216 | 0.77 | MEN1 (0.56) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL23997331 | 0.76 | MEN1 (0.54) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL25234619 | 0.76 | MEN1 (0.54) | MEN1KMT2AL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146644-A1 | IL4I1 INHIBITORS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2023-03-15 | — | — | EP | disclosed |