Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 14/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017158 | 1.00 | GLS (0.62) | GLSPIM1PIM3PIM2 | |
| SCHEMBL29017138 | 1.00 | GLS (0.62) | GLSPIM1PIM3PIM2 | |
| SCHEMBL30336987 | 0.84 | CCNA2 (0.52) | GLS | |
| SCHEMBL29017136 | 0.84 | CCNA2 (0.52) | GLS | |
| SCHEMBL29017123 | 0.84 | CCNA2 (0.52) | GLS | |
| SCHEMBL18890243 | 0.77 | GLS (1.00) | GLS | |
| SCHEMBL21045733 | 0.77 | GLS (1.00) | GLS | |
| SCHEMBL18890242 | 0.77 | GLS (1.00) | GLS | |
| SCHEMBL29017176 | 0.76 | GLS (0.74) | GLS | |
| SCHEMBL29017213 | 0.74 | GLS (0.43) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594683-A | Glutaminase GLS1 inhibitor and preparation method and application thereof | 杭州禹胜医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |