Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 18/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.41 |
| ▸ | ITGAL | P20701 | 18/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019150 | 1.00 | ITGB2 (0.41) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL29019149 | 1.00 | ITGB2 (0.41) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL29019143 | 0.94 | ITGB2 (0.46) | ITGB2ICAM1ITGAL | |
| SCHEMBL29019142 | 0.94 | ITGB2 (0.46) | ITGB2ICAM1ITGAL | |
| SCHEMBL24805349 | 0.86 | ITGB2 (0.43) | ITGB2ICAM1ITGAL | |
| SCHEMBL26104804 | 0.86 | ITGB2 (0.43) | ITGB2ICAM1ITGAL | |
| SCHEMBL23978556 | 0.86 | ITGB2 (0.43) | ITGB2ICAM1ITGAL | |
| SCHEMBL30279378 | 0.86 | ITGB2 (0.43) | ITGB2ICAM1ITGAL | |
| SCHEMBL23978993 | 0.81 | ITGB2 (0.44) | ITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL24803248 | 0.81 | ITGB2 (0.44) | ITGB2ICAM1ITGALALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916176-A | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |