Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 5/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 4/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 2/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28384419 | 1.00 | DYRK1A (0.46) | DYRK1ADYRK1BGSK3BMKNK1MKNK2 | |
| SCHEMBL28987624 | 0.89 | DYRK1A (0.43) | DYRK1ADYRK1BGSK3BMKNK1MKNK2 | |
| SCHEMBL30337437 | 0.89 | DYRK1A (0.43) | DYRK1ADYRK1BGSK3BMKNK1MKNK2 | |
| SCHEMBL19254846 | 0.88 | DYRK1A (0.45) | DYRK1ADYRK1BGSK3BMKNK1MKNK2 | |
| SCHEMBL17490471 | 0.88 | DYRK1A (0.45) | DYRK1ADYRK1BGSK3BMKNK1MKNK2 | |
| SCHEMBL30337212 | 0.88 | DYRK1A (0.45) | DYRK1ADYRK1BGSK3BMKNK1MKNK2 | |
| SCHEMBL17683321 | 0.86 | DYRK1A (0.44) | DYRK1ADYRK1BGSK3BMKNK1MKNK2 | |
| SCHEMBL30459718 | 0.86 | DYRK1A (0.44) | DYRK1ADYRK1BGSK3BMKNK1MKNK2 | |
| SCHEMBL30337177 | 0.84 | DYRK1A (0.44) | DYRK1ADYRK1BGSK3BMKNK1MKNK2 | |
| SCHEMBL28987593 | 0.84 | DYRK1A (0.44) | DYRK1ADYRK1BGSK3BMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974845-B | Preparation method of Ornitinib intermediate | 奥锐特药业股份有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-115974845-A | Preparation method of oxitinib intermediate | 奥锐特药业股份有限公司 | 2023-04-18 | — | — | CN | disclosed |